The Flemish giant rabbit, also known as Oryctolagus cuniculus domesticus, is one of the largest breeds of rabbits. This docile species was domesticated in the early 16th century and has been bred ever since. It was first bred in Ghent, a city in Belgium, and although the records are a little hazy, the first written account put it on the map in 1860. Flemish giants were historically bred for their meat and fur.